SCHEMBL18538549

SCHEMBL18538549

CNC1CC(=O)N(c2ccc(Oc3ccc(C(C)(C)c4ccc(Oc5ccc(N6C(=O)C=CC6=O)cc5)cc4)cc3)cc2)C1=O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.44
ALDH1A1 P00352 6/20 0.43
MAPT P10636 5/20 0.43
KMT2A Q03164 2/20 0.43
GAA P10253 1/20 0.43
MEN1 O00255 1/20 0.43
HTT P42858 1/20 0.39
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15875894 0.81 MGLL (0.64) MGLLALDH1A1KMT2AMEN1HTT
SCHEMBL485546 0.81 MGLL (0.64) MGLLALDH1A1KMT2AMEN1HTT
SCHEMBL94891 0.81 MGLL (0.64) MGLLALDH1A1KMT2AMEN1HTT
SCHEMBL18859867 0.79 MGLL (0.54) MGLLALDH1A1KMT2AGAAMEN1
SCHEMBL18538548 0.78 MGLL (0.58) MGLLALDH1A1MAPTKMT2AGAA
SCHEMBL24541383 0.76 MGLL (0.70) MGLLALDH1A1MAPTKMT2AMEN1
SCHEMBL24753819 0.76 MGLL (0.61) MGLLALDH1A1KMT2AMEN1HTT
SCHEMBL487831 0.74 MGLL (0.58) MGLLALDH1A1KMT2AMEN1HTT
SCHEMBL26452127 0.74 MGLL (0.54) MGLLALDH1A1KMT2AMEN1HTT
SCHEMBL8766700 0.73 MGLL (0.53) MGLLALDH1A1KMT2AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11008420-B2 Resin composition, prepreg, metal foil-clad laminate, resin composite sheet, and printed wiring board MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-05-18 US disclosed
US-20210032404-A1 RESIN COMPOSITION, PREPREG, METAL FOIL-CLAD LAMINATE, RESIN COMPOSITE SHEET, AND PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-02-04 US disclosed
EP-3290480-B1 RESIN COMPOSITION, PREPREG, LAMINATE AND MULTILAYER PRINTED WIRING BOARD SHOWA DENKO MATERIALS CO LTD (JP) 2020-12-09 EP disclosed
US-20180134842-A1 RESIN COMPOSITION, PREPREG, LAMINATE AND MULTILAYER PRINTED WIRING BOARD RESONAC CORPORATION (JP) 2018-05-17 US disclosed
US-20180127547-A1 THERMOSETTING RESIN COMPOSITION, PREPREG, LAMINATE AND MULTILAYER PRINTED WIRING BOARD RESONAC CORPORATION (JP) 2018-05-10 US disclosed
EP-3290480-A1 RESIN COMPOSITION, PREPREG, LAMINATE AND MULTILAYER PRINTED WIRING BOARD Hitachi Chemical Company, Ltd. (JP) 2018-03-07 EP disclosed
US-9828466-B2 Polyphenylene ether derivative having N-substituted maleimide group, and heat curable resin composition, resin varnish, prepreg, metal-clad laminate, and multilayer printed wiring board using same HITACHI CHEMICAL COMPANY, LTD (JP) 2017-11-28 US disclosed
US-9828466-B2 Polyphenylene ether derivative having N-substituted maleimide group, and heat curable resin composition, resin varnish, prepreg, metal-clad laminate, and multilayer printed wiring board using same HITACHI CHEMICAL COMPANY, LTD (JP) 2017-11-28 US disclosed
US-20170051109-A1 POLYPHENYLENE ETHER DERIVATIVE HAVING N-SUBSTITUTED MALEIMIDE GROUP, AND HEAT CURABLE RESIN COMPOSITION, RESIN VARNISH, PREPREG, METAL-CLAD LAMINATE, AND MULTILAYER PRINTED WIRING BOARD USING SAME HITACHI CHEMICAL COMPANY, LTD. (JP) 2017-02-23 US disclosed
US-20170051109-A1 POLYPHENYLENE ETHER DERIVATIVE HAVING N-SUBSTITUTED MALEIMIDE GROUP, AND HEAT CURABLE RESIN COMPOSITION, RESIN VARNISH, PREPREG, METAL-CLAD LAMINATE, AND MULTILAYER PRINTED WIRING BOARD USING SAME HITACHI CHEMICAL COMPANY, LTD. (JP) 2017-02-23 US disclosed