SCHEMBL18539720

SCHEMBL18539720

CCC(=O)O/N=C/c1cn(C)c2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.51
GAA P10253 3/20 0.51
ATM Q13315 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ALDH1A1 P00352 5/20 0.50
IMPDH2 P12268 1/20 0.50
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
KDM4E B2RXH2 4/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.48
LMNA P02545 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
HPGD P15428 3/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL213761 0.85 MAPT (0.54) MAPTGAAATMNPSR1ALDH1A1
SCHEMBL213762 0.85 MAPT (0.54) MAPTGAAATMNPSR1ALDH1A1
SCHEMBL18539727 0.82 ALDH1A1 (0.48) MAPTGAANPSR1ALDH1A1MEN1
SCHEMBL18539626 0.82 MAPT (0.56) MAPTGAAATMNPSR1ALDH1A1
SCHEMBL212575 0.77 KMT2A (0.57) MAPTGAAATMNPSR1ALDH1A1
SCHEMBL212576 0.77 KMT2A (0.57) MAPTGAAATMNPSR1ALDH1A1
SCHEMBL212097 0.75 MAPT (0.50) MAPTGAAATMNPSR1ALDH1A1
SCHEMBL212098 0.75 MAPT (0.50) MAPTGAAATMNPSR1ALDH1A1
SCHEMBL18539718 0.74 NR4A2 (0.52) MAPTNPSR1ALDH1A1KMT2ALMNA
SCHEMBL9668380 0.74 MAPT (0.51) MAPTGAAATMNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3438134-B1 POLYMERIZABLE COMPOSITION, CURED OBJECT, OPTICAL FILM FOR DISPLAY, AND PROCESS FOR PRODUCING CURED OBJECT ADEKA CORP (JP) 2021-05-05 EP disclosed
EP-3438134-A1 POLYMERIZABLE COMPOSITION, CURED OBJECT, OPTICAL FILM FOR DISPLAY, AND PROCESS FOR PRODUCING CURED OBJECT Adeka Corporation (JP) 2019-02-06 EP disclosed
US-10189847-B2 Oxime ester compound and photopolymerization initiator containing said compound ADEKA CORPORATION (JP) 2019-01-29 US disclosed
US-20170166575-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING SAID COMPOUND ADEKA CORPORATION (JP) 2017-06-15 US disclosed
US-20170166575-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING SAID COMPOUND ADEKA CORPORATION (JP) 2017-06-15 US disclosed
WO-2017030005-A1 COMPOSITION 株式会社ADEKA 2017-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170166575-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING SAID COMPOUND RB1, PRMT9, KDM2B MAPT 3454/4885GAA 3469/4885ATM 1447/4885
US-10189847-B2 Oxime ester compound and photopolymerization initiator containing said compound PPOX, CCNO, MRTO4 MAPT 2515/4885GAA 2687/4885ATM 1377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.