Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18549308 | 0.82 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL18539734 | 0.79 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL18549710 | 0.79 | MAPT (0.35) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL18539735 | 0.79 | MAPT (0.36) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL18539732 | 0.76 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL27517945 | 0.73 | PDE4B (0.47) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL18539736 | 0.71 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL6409483 | 0.71 | L3MBTL1 (0.50) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL27946093 | 0.71 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL31437277 | 0.70 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170050934-A1 | ETHERIC (ETHEREAL) OXYGEN ATOM-CONTAINING PERFLUOROALKYL GROUP-SUBSTITUTED PYRIMIDINE RING COMPOUND, AND METHOD FOR ITS PRODUCTION | ASAHI GLASS COMPANY, LIMITED (JP) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050934-A1 | ETHERIC (ETHEREAL) OXYGEN ATOM-CONTAINING PERFLUOROALKYL GROUP-SUBSTITUTED PYRIMIDINE RING COMPOUND, AND METHOD FOR ITS PRODUCTION | CYP2B6, PFAS, CYP2F1 | ALDH1A1 1430/4885SMN1; SMN2 4379/4885RAB9A 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.