Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.55 |
| ▸ | ITGAV | P06756 | 1/20 | 0.55 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 4/20 | 0.52 |
| ▸ | CCKAR | P32238 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464196 | 0.92 | OPRM1 (0.60) | OPRD1OPRM1KDM4EMEN1LMNA | |
| SCHEMBL30974288 | 0.87 | CCKAR (0.57) | OPRD1OPRM1ITGB3ITGB1ITGAV | |
| SCHEMBL26605065 | 0.87 | KDM4E (0.60) | OPRD1OPRM1KDM4EMEN1LMNA | |
| SCHEMBL26605070 | 0.87 | KDM4E (0.60) | OPRD1OPRM1KDM4EMEN1LMNA | |
| SCHEMBL16317501 | 0.87 | KDM4E (0.65) | KDM4EMEN1LMNAMPOMAPT | |
| SCHEMBL18541537 | 0.87 | KDM4E (0.65) | KDM4EMEN1LMNAMPOMAPT | |
| SCHEMBL29378473 | 0.87 | KDM4E (0.65) | KDM4EMEN1LMNAMPOMAPT | |
| SCHEMBL29828681 | 0.86 | KDM4E (0.57) | OPRD1OPRM1KDM4EMEN1LMNA | |
| SCHEMBL30052764 | 0.86 | KDM4E (0.62) | OPRD1OPRM1KDM4EMEN1LMNA | |
| SCHEMBL30974299 | 0.85 | ACE (0.58) | OPRD1OPRM1KDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017030859-A1 | CCK2R-DRUG CONJUGATES | ENDOCYTE, INC. (US) | 2017-02-23 | — | — | WO | disclosed |