Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | NMBR | P28336 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | TACR3 | P29371 | 1/20 | 0.50 |
| ▸ | BRS3 | P32247 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18541554 | 0.92 | OPRD1 (0.56) | OPRM1OPRD1KDM4EMEN1LMNA | |
| SCHEMBL26605065 | 0.90 | KDM4E (0.60) | OPRM1OPRD1KDM4EMEN1LMNA | |
| SCHEMBL26605070 | 0.90 | KDM4E (0.60) | OPRM1OPRD1KDM4EMEN1LMNA | |
| SCHEMBL18541537 | 0.90 | KDM4E (0.65) | KDM4EMEN1LMNAMPOMAPT | |
| SCHEMBL16317501 | 0.90 | KDM4E (0.65) | KDM4EMEN1LMNAMPOMAPT | |
| SCHEMBL29378473 | 0.90 | KDM4E (0.65) | KDM4EMEN1LMNAMPOMAPT | |
| SCHEMBL30052764 | 0.89 | KDM4E (0.62) | OPRM1OPRD1KDM4EMEN1LMNA | |
| SCHEMBL5178667 | 0.88 | CTSL (0.54) | OPRM1OPRD1CTSLNMBRTACR1 | |
| SCHEMBL26605057 | 0.88 | CTSL (0.54) | OPRM1OPRD1CTSLNMBRTACR1 | |
| SCHEMBL30464831 | 0.87 | OPRM1 (0.64) | OPRM1OPRD1BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183358-A1 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE | THE BURNHAM INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |