Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865471 | 0.80 | CRBN (0.44) | MEN1KMT2AMAPTATMRAB9A | |
| SCHEMBL10854504 | 0.79 | HTT (0.41) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL10857201 | 0.79 | HTT (0.41) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL19744326 | 0.79 | CRBN (0.46) | KMT2AALDH1A1MAPTHTTATM | |
| SCHEMBL19744406 | 0.79 | CRBN (0.46) | KMT2AALDH1A1MAPTHTTATM | |
| SCHEMBL14510166 | 0.78 | CRBN (0.38) | ALDH1A1MAPTATMRAB9ASMN1; SMN2 | |
| SCHEMBL14510164 | 0.78 | CRBN (0.38) | ALDH1A1MAPTATMRAB9ASMN1; SMN2 | |
| SCHEMBL2042093 | 0.77 | RAB9A (0.50) | ALDH1A1TSHRRAB9ASMN1; SMN2HPGD | |
| SCHEMBL31372524 | 0.77 | RAB9A (0.50) | ALDH1A1TSHRRAB9ASMN1; SMN2HPGD | |
| SCHEMBL19493715 | 0.77 | RAB9A (0.50) | ALDH1A1TSHRRAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017030684-A1 | DEHYDRATIVE CYCLIZATION OF PENTITOLS USING WATER-TOLERANT LEWIS ACID CATALYSTS UNDER MILD CONDITIONS AND DERIVATIVES | ARCHER DANIELS MIDLAND COMPANY (US) | 2017-02-23 | — | — | WO | disclosed |