Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19744326 | 1.00 | CRBN (0.46) | CRBNSLC6A2SLC6A4SLC6A3CYP2C19 | |
| SCHEMBL10865471 | 0.82 | CRBN (0.44) | CRBNCYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18541672 | 0.79 | MEN1 (0.48) | CRBNCYP2C19CYP1A2CYP2C9NPC1 | |
| SCHEMBL14510164 | 0.73 | CRBN (0.38) | CRBNCYP2C19L3MBTL1NPC1GAA | |
| SCHEMBL14510166 | 0.73 | CRBN (0.38) | CRBNCYP2C19L3MBTL1NPC1GAA | |
| SCHEMBL7766815 | 0.73 | CRBN (0.43) | CRBNCYP2C19CYP3A4L3MBTL1NPC1 | |
| SCHEMBL7767198 | 0.72 | CRBN (0.49) | CRBNCYP2C19CYP2C9L3MBTL1NPC1 | |
| SCHEMBL1402328 | 0.71 | HDAC1 (0.36) | CRBNCYP3A4RAB9AALDH1A1KMT2A | |
| SCHEMBL8940654 | 0.71 | CRBN (0.39) | CRBNCYP2C19L3MBTL1NPC1GAA | |
| SCHEMBL206 | 0.71 | CYP2C19 (0.56) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017222532-A1 | PREPARATION OF MONO- AND DI-ALKYL HALIDE FURANIC COMPOUNDS FROM 2,5-BIS(HYDROXYMETHYL)-TETRAHYDROFURANS (BHMTHF) AND DERIVATIVES THEREOF | ARCHER DANIELS MIDLAND COMPANY (US) | 2017-12-28 | — | — | WO | disclosed |