Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24846085 | 0.88 | TSHR (0.57) | TSHRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL24846592 | 0.79 | KMT2A (0.45) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL24846593 | 0.78 | KMT2A (0.45) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL18542001 | 0.75 | RAB9A (0.43) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL18542002 | 0.75 | MEN1 (0.38) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL18542085 | 0.74 | MAPT (0.67) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL18541999 | 0.71 | GLA (0.38) | TSHRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL12793836 | 0.71 | RXFP1 (0.77) | TSHRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL24846070 | 0.70 | TSHR (0.61) | TSHRMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24846080 | 0.70 | TSHR (0.57) | TSHRMEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017029498-A1 | 2-SULFONYLPYRIMIDINES | MEDICAL RESEARCH COUNCIL (GB) | 2017-02-23 | — | — | WO | disclosed |