Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19157898 | 0.87 | IDO1 (0.42) | MEN1KMT2AGRIN1GRIN2BMPO | |
| SCHEMBL18542001 | 0.84 | RAB9A (0.43) | MEN1KMT2AGRIN1GRIN2BMPO | |
| SCHEMBL20724171 | 0.81 | DPP4 (0.33) | MEN1KMT2AGRIN1GRIN2BALDH1A1 | |
| SCHEMBL18541999 | 0.80 | GLA (0.38) | MEN1KMT2AGRIN1GRIN2BMPO | |
| SCHEMBL19225348 | 0.79 | ALDH1A1 (0.36) | MEN1KMT2AGRIN1GRIN2BRIPK1 | |
| SCHEMBL20724194 | 0.76 | ALDH1A1 (0.40) | MEN1KMT2AGRIN1GRIN2BALDH1A1 | |
| SCHEMBL12188089 | 0.76 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL18542004 | 0.75 | TSHR (0.56) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL24846085 | 0.73 | TSHR (0.57) | MEN1KMT2AHSD17B10ALDH1A1NPC1 | |
| SCHEMBL20340996 | 0.73 | MEP1B (0.39) | MEN1KMT2AHSD17B10GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017029498-A1 | 2-SULFONYLPYRIMIDINES | MEDICAL RESEARCH COUNCIL (GB) | 2017-02-23 | — | — | WO | disclosed |