Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16016319 | 0.87 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL18542002 | 0.84 | MEN1 (0.38) | RAB9ANPC1SMN1; SMN2GRIN1GRIN2B | |
| SCHEMBL19157827 | 0.81 | RAB9A (0.35) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL18541999 | 0.80 | GLA (0.38) | RAB9ANPC1GRIN1GRIN2BMEN1 | |
| SCHEMBL19157476 | 0.79 | GRIN2B (0.37) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL19157860 | 0.76 | ALDH1A1 (0.40) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL14140247 | 0.76 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL18542004 | 0.75 | TSHR (0.56) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL19157475 | 0.75 | HDAC6 (0.36) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL24846085 | 0.73 | TSHR (0.57) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017029498-A1 | 2-SULFONYLPYRIMIDINES | MEDICAL RESEARCH COUNCIL (GB) | 2017-02-23 | — | — | WO | disclosed |