Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 13/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849270 | 0.80 | NMT1 (0.67) | NMT1LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL1868795 | 0.79 | NMT1 (0.70) | NMT1LMNAHTTSMN1; SMN2 | |
| SCHEMBL3232564 | 0.74 | ALDH1A3 (0.44) | FFAR4 | |
| SCHEMBL16509583 | 0.73 | NMT1 (0.70) | NMT1LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL1857012 | 0.71 | NMT1 (0.69) | NMT1L3MBTL1 | |
| SCHEMBL16502948 | 0.70 | LMNA (0.66) | NMT1LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL13457978 | 0.70 | LMNA (0.66) | NMT1LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL16817058 | 0.69 | LMNA (0.71) | NMT1LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL16502992 | 0.69 | LMNA (0.71) | NMT1LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL18002608 | 0.69 | ALDH1A3 (0.51) | LMNAHTTSMN1; SMN2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323987-A1 | N-MYRISTOYL TRANSFERASE INHIBITORS | University of Dundee (GB) | 2011-05-25 | — | — | EP | disclosed |