Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246944 | 0.82 | TSHR (0.53) | TSHRLMNAADRB2ADRB1PNMT | |
| Hydrochloric Acid SCHEMBL2155084 | 0.79 | TSHR (0.50) | TSHRLMNAADRB2ADRB1PNMT | |
| 1,2-Dichlorobenzene SCHEMBL27492790 | 0.69 | TSHR (0.67) | TSHRLMNAPNMTIDO1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2154232 | 0.67 | TSHR (0.41) | TSHRLMNAPNMTIDO1ALDH1A1 | |
| SCHEMBL8013185 | 0.67 | TSHR (0.36) | TSHRLMNAADRB2ADRB1ALDH1A1 | |
| SCHEMBL4899299 | 0.66 | TSHR (0.45) | TSHRLMNAPNMTIDO1ALDH1A1 | |
| 1,2-Dichlorobenzene SCHEMBL28151921 | 0.66 | TSHR (0.71) | TSHRLMNAPNMTIDO1ALDH1A1 | |
| 1,2-Dichlorobenzene SCHEMBL27583458 | 0.63 | TSHR (0.67) | TSHRLMNAPNMTIDO1ALDH1A1 | |
| SCHEMBL27879783 | 0.62 | — | — | |
| SCHEMBL10712310 | 0.62 | TSHR (0.41) | TSHRLMNAADRB2ADRB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180244865-A1 | INCREASED EFFICIENCY DESULFURIZATION REAGENTS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-08-30 | — | — | US | disclosed |
| EP-3341432-A1 | INCREASED EFFICIENCY DESULFURIZATION REAGENTS | ARLANXEO Deutschland GmbH (DE) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017036721-A1 | INCREASED EFFICIENCY DESULFURIZATION REAGENTS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-03-09 | — | — | WO | disclosed |
| EP-3135712-A1 | INCREASED EFFICIENCY OF DESULFURIZATION REAGENTS | ARLANXEO Deutschland GmbH (DE) | 2017-03-01 | — | — | EP | disclosed |