Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246944 | 0.75 | TSHR (0.53) | TSHRLMNAIDO1PNMTALDH1A1 | |
| Hydrochloric Acid SCHEMBL2155084 | 0.72 | TSHR (0.50) | TSHRLMNAIDO1PNMTALDH1A1 | |
| SCHEMBL9441833 | 0.68 | TSHR (0.45) | TSHRLMNAALDH1A1TAAR1CYP2A6 | |
| SCHEMBL8745400 | 0.67 | TSHR (0.43) | TSHRLMNAIDO1PNMTALDH1A1 | |
| SCHEMBL18544199 | 0.66 | TSHR (0.36) | TSHRLMNAIDO1PNMTALDH1A1 | |
| 1,2-Dichlorobenzene SCHEMBL1155123 | 0.65 | TSHR (1.00) | TSHRLMNAIDO1PNMTALDH1A1 | |
| 1,2-Dichlorobenzene SCHEMBL29350623 | 0.65 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL10593125 | 0.65 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL5190 | 0.65 | — | — | |
| SCHEMBL3388879 | 0.65 | GABRA1 (0.41) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404915-B2 | 1) at least one diaryl-substituted diphosphine ligand; 2) a chromium metal precursor; and 3) optionally, one or more activators | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-20080058486-A1 | Phosphine Ligand-Metal Compositions, Complexes, and Catalysts For Ethylene Trimerizations | SYMYX TECHNOLOGIES INC. | 2008-03-06 | — | — | US | disclosed |