SCHEMBL8013185

SCHEMBL8013185

Cc1ccc(Pc2ccccc2Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
LMNA P02545 2/20 0.36
RAB9A P51151 3/20 0.36
NPC1 O15118 2/20 0.36
ACHE P22303 3/20 0.35
ALOX12 P18054 1/20 0.35
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 3/20 0.32
HPGD P15428 3/20 0.32
ALDH1A1 P00352 3/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD11B1 P28845 1/20 0.31
ADRB2 P07550 1/20 0.30
ADRB1 P08588 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8745400 0.82 TSHR (0.43) TSHRLMNAALDH1A1
Hydrochloric Acid SCHEMBL2154232 0.80 TSHR (0.41) TSHRLMNAALDH1A1
SCHEMBL11311009 0.78 ACHE (0.39) TSHRLMNAACHEALOX12TDP1
SCHEMBL246944 0.77 TSHR (0.53) TSHRLMNAALDH1A1ADRB2ADRB1
SCHEMBL10079348 0.75 ACHE (0.42) TSHRLMNARAB9ANPC1ACHE
SCHEMBL8004958 0.75 ACHE (0.35) TSHRLMNAACHEALOX12TDP1
Hydrochloric Acid SCHEMBL2155084 0.74 TSHR (0.50) TSHRLMNAALDH1A1ADRB2ADRB1
SCHEMBL2933392 0.72 ACHE (0.53) TSHRLMNARAB9ANPC1ACHE
SCHEMBL5401678 0.72 CYP2A6 (0.43) TSHRRAB9ANPC1TDP1L3MBTL1
SCHEMBL11312200 0.72 GABRA1 (0.34) TSHRLMNARAB9ANPC1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924561-A Transition metal catalyst, preparation method thereof, intermediate and application 中国石油化工股份有限公司 2024-04-26 CN disclosed
US-6031066-A POLYMERIZING ALPHA, BETA-UNSATURATED CARBOXYLIC ACID ESTER CONTAINING A TERTIARY AMINO GROUP AS A POLYMERIZABLE MONOMER IN THE PRESENCE OF A PHOSPHORUS COMPOUND DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-02-29 US disclosed