SCHEMBL18544264

SCHEMBL18544264

COc1cnc2ncc(Cl)c(I)c2n1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20687536 0.78 NPBWR1 (0.31) CNR2
SCHEMBL18544276 0.76 PDGFRB (0.36)
SCHEMBL30519743 0.66 CNR2 (0.42) CNR2
SCHEMBL29687133 0.66 LMNA (0.33)
SCHEMBL17681852 0.66 LMNA (0.33)
SCHEMBL25347775 0.66 CNR2 (0.42) CNR2
SCHEMBL21395383 0.65 F2RL3 (0.34)
SCHEMBL3618668 0.65 CSF1R (0.35)
SCHEMBL17325899 0.64 ADORA3 (0.35)
SCHEMBL19776485 0.64 F2RL3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017029602-A2 COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2017-02-23 WO disclosed