Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 7/20 | 0.50 |
| ▸ | BCHE | P06276 | 6/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18544340 | 1.00 | FDPS (0.52) | FDPSKDM4EACHEBCHENFE2L2 | |
| SCHEMBL18544332 | 0.94 | FDPS (0.53) | FDPSKDM4EACHEBCHENFE2L2 | |
| SCHEMBL18544333 | 0.94 | FDPS (0.53) | FDPSKDM4EACHEBCHENFE2L2 | |
| SCHEMBL18544352 | 0.86 | NFE2L2 (0.56) | FDPSKDM4EACHEBCHENFE2L2 | |
| SCHEMBL18544353 | 0.86 | NFE2L2 (0.56) | FDPSKDM4EACHEBCHENFE2L2 | |
| SCHEMBL18570142 | 0.80 | FDPS (0.61) | FDPSKDM4EACHENFE2L2APP | |
| SCHEMBL3003951 | 0.80 | NFE2L2 (0.71) | KDM4ENFE2L2APPKMT2AALDH1A1 | |
| SCHEMBL3003953 | 0.80 | NFE2L2 (0.71) | KDM4ENFE2L2APPKMT2AALDH1A1 | |
| SCHEMBL20906899 | 0.79 | FDPS (0.62) | FDPSKDM4EACHENFE2L2APP | |
| SCHEMBL24080309 | 0.78 | FDPS (0.59) | FDPSKDM4ENFE2L2APPSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3135110-A1 | 1,7-DIARYL-1,6-HEPTADIEN-3,5-DION DERIVATIVES, METHODS OF MAKING AND USING THE SAME | Universitätsklinikum Regensburg (DE) | 2017-03-01 | — | — | EP | disclosed |