Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | PTGES | O14684 | 4/20 | 0.55 |
| ▸ | FDPS | P14324 | 3/20 | 0.55 |
| ▸ | APP | P05067 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 5/20 | 0.52 |
| ▸ | BCHE | P06276 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18544353 | 1.00 | NFE2L2 (0.56) | NFE2L2PTGESFDPSAPPACHE | |
| SCHEMBL18544332 | 0.86 | FDPS (0.53) | NFE2L2PTGESFDPSAPPACHE | |
| SCHEMBL18544333 | 0.86 | FDPS (0.53) | NFE2L2PTGESFDPSAPPACHE | |
| SCHEMBL18544340 | 0.86 | FDPS (0.52) | NFE2L2PTGESFDPSAPPACHE | |
| SCHEMBL18544341 | 0.86 | FDPS (0.52) | NFE2L2PTGESFDPSAPPACHE | |
| SCHEMBL20506818 | 0.78 | FDPS (0.59) | NFE2L2PTGESFDPSAPPKDM4E | |
| SCHEMBL18544316 | 0.78 | NFE2L2 (0.56) | NFE2L2PTGESFDPSAPPKDM4E | |
| SCHEMBL18544315 | 0.78 | NFE2L2 (0.56) | NFE2L2PTGESFDPSAPPKDM4E | |
| SCHEMBL1929620 | 0.76 | KDM4E (0.48) | FDPSACHEBCHEKDM4E | |
| SCHEMBL21218182 | 0.75 | NFE2L2 (0.74) | NFE2L2PTGESFDPSAPPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3135110-B1 | 1,7-DIARYL-1,6-HEPTADIEN-3,5-DION DERIVATIVES, METHODS OF MAKING AND USING THE SAME | TRIOPTOTEC GMBH (DE) | 2019-07-10 | — | — | EP | disclosed |
| WO-2017032892-A1 | 1,7-DIARYL-1,6-HEPTADIENE-3,5-DIONE DERIVATIVES, METHODS FOR THE PRODCUTION AND USE THEREOF | UNIVERSITÄTSKLINIKUM REGENSBURG (DE) | 2017-03-02 | — | — | WO | disclosed |
| EP-3135110-A1 | 1,7-DIARYL-1,6-HEPTADIEN-3,5-DION DERIVATIVES, METHODS OF MAKING AND USING THE SAME | Universitätsklinikum Regensburg (DE) | 2017-03-01 | — | — | EP | disclosed |