Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 14/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849577 | 0.87 | GPR52 (0.51) | GPR52ADORA2ALTA4HTAAR1IDO1 | |
| SCHEMBL13506352 | 0.76 | GPR52 (0.53) | GPR52ADORA2ALTA4HTAAR1IDO1 | |
| SCHEMBL1849646 | 0.76 | GPR52 (0.48) | GPR52TAAR1 | |
| SCHEMBL1855052 | 0.75 | TAAR1 (0.47) | GPR52TAAR1IDO1 | |
| SCHEMBL3198362 | 0.75 | GPR52 (0.61) | GPR52ADORA2A | |
| SCHEMBL13505746 | 0.73 | GPR52 (0.48) | GPR52ADORA2ALTA4HTAAR1 | |
| SCHEMBL1852612 | 0.73 | GPR52 (0.48) | GPR52TAAR1 | |
| SCHEMBL1852707 | 0.73 | GPR52 (0.56) | GPR52 | |
| SCHEMBL13506123 | 0.72 | GPR52 (0.55) | GPR52 | |
| SCHEMBL1856450 | 0.72 | GPR52 (0.62) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | GPR52 1/4885ADORA2A 212/4885LTA4H 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.