Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18544429 | 1.00 | DPP4 (0.47) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL16399329 | 1.00 | DPP4 (0.47) | DPP4CTSLCTSBCTSKOPRM1 | |
| Hydrochloric Acid SCHEMBL17685953 | 0.98 | DPP4 (0.46) | DPP4CTSLCTSBCTSKOPRM1 | |
| Hydrochloric Acid SCHEMBL17685955 | 0.98 | DPP4 (0.46) | DPP4CTSLCTSBCTSKOPRM1 | |
| Hydrochloric Acid SCHEMBL17685951 | 0.98 | DPP4 (0.46) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL18506691 | 0.85 | DPP4 (0.55) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL8345616 | 0.83 | CTSL (0.46) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL20621138 | 0.81 | CTSL (0.45) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL8053071 | 0.81 | DPP4 (0.51) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL3818209 | 0.80 | OPRM1 (0.47) | DPP4CTSLCTSBCTSKOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004084-B1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma AG (DE) | 2017-03-01 | — | — | EP | disclosed |