Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345616 | 0.90 | CTSL (0.46) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL27229751 | 0.82 | CTSL (0.40) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL18544429 | 0.81 | DPP4 (0.47) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL22501954 | 0.81 | CTSL (0.44) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL3818209 | 0.81 | OPRM1 (0.47) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL18544430 | 0.81 | DPP4 (0.47) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL16399329 | 0.81 | DPP4 (0.47) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL22029580 | 0.81 | CARM1 (0.46) | DPP4CTSLCTSBCTSKOPRM1 | |
| SCHEMBL27229703 | 0.81 | BCHE (0.40) | DPP4CTSLCTSBCTSKOPRM1 | |
| Hydrochloric Acid SCHEMBL17685951 | 0.79 | DPP4 (0.46) | DPP4CTSLCTSBCTSKOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080750-A | FOR PROPHYLAXIS AND TREATMENT OF DISEASES CAUSED BY INFECTION BY ROTAVIRUS | NIPPON SHOJI KAISHA LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0806418-A2 | Novel pyrimidine compound and anti-rotavirus agent | NIPPON SHOJI KAISHA, LIMITED (JP) | 1997-11-12 | — | — | EP | disclosed |