⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13464406 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL23899653 | 0.69 | — | — | |
| SCHEMBL19312770 | 0.68 | — | — | |
| SCHEMBL22302360 | 0.65 | — | — | |
| SCHEMBL24543447 | 0.64 | — | — | |
| SCHEMBL3573704 | 0.63 | — | — | |
| SCHEMBL22259090 | 0.62 | LMNA (0.32) | — | |
| SCHEMBL13464355 | 0.62 | — | — | |
| SCHEMBL19413009 | 0.62 | — | — | |
| SCHEMBL9301370 | 0.61 | L3MBTL1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10039762-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-08-07 | — | — | US | disclosed |
| US-10008300-B2 | Method for eliminating radioactive iodine and hydrophilic resin for eliminating radioactive iodine | DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) | 2018-06-26 | — | — | US | disclosed |
| US-20180078553-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED | 2018-03-22 | — | — | US | disclosed |
| US-9905768-B2 | Semiconductor device and insulating layer-forming composition | FUJIFILM CORPORATION (JP) | 2018-02-27 | — | — | US | disclosed |
| EP-3141252-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20170054076-A1 | SEMICONDUCTOR DEVICE AND INSULATING LAYER-FORMING COMPOSITION | FUJIFILM CORPORATION (JP) | 2017-02-23 | — | — | US | disclosed |