Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743084 | 0.78 | OPRL1 (0.46) | OPRL1 | |
| SCHEMBL17151565 | 0.73 | OPRL1 (0.47) | OPRL1BACE1 | |
| SCHEMBL25555029 | 0.73 | SLC6A2 (0.43) | OPRL1 | |
| SCHEMBL1356638 | 0.70 | OPRL1 (0.53) | OPRL1 | |
| SCHEMBL9049881 | 0.70 | OPRL1 (0.49) | OPRL1BACE1 | |
| SCHEMBL2042478 | 0.69 | OPRL1 (0.51) | OPRL1 | |
| Alcohol SCHEMBL6978627 | 0.67 | OPRL1 (0.47) | OPRL1 | |
| SCHEMBL13229274 | 0.67 | OPRL1 (0.57) | OPRL1 | |
| SCHEMBL1355838 | 0.67 | OPRL1 (0.40) | OPRL1BACE1 | |
| SCHEMBL12776380 | 0.67 | NPC1 (0.46) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170050942-A1 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORP (US) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050942-A1 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | CCR2, CCR5, CXCR3 | OPRL1 242/4885BACE1 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.