SCHEMBL1854492

SCHEMBL1854492

CCO[SiH](CNc1ccccc1)OCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.40
ALDH1A1 P00352 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GAA P10253 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
TAS2R38 P59533 1/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
NAPRT Q6XQN6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1857812 0.85 HPGD (0.42) MAPTALDH1A1NPSR1GAAL3MBTL1
SCHEMBL774108 0.81 MAPT (0.47) MAPTALDH1A1NPSR1GAAL3MBTL1
SCHEMBL980165 0.79 MAPT (0.43) MAPTALDH1A1L3MBTL1LMNATSHR
SCHEMBL483772 0.78 ALDH1A1 (0.53) MAPTALDH1A1NPSR1GAAL3MBTL1
SCHEMBL722359 0.77 ALDH1A1 (0.52) MAPTALDH1A1NPSR1L3MBTL1CYP1A2
SCHEMBL25403135 0.75 ALDH1A1 (0.50) MAPTALDH1A1NPSR1L3MBTL1HTT
SCHEMBL15360416 0.75 ALDH1A1 (0.50) MAPTALDH1A1NPSR1L3MBTL1HTT
SCHEMBL15135242 0.73 MEN1 (0.47) MAPTGAAMEN1CYP3A4KMT2A
SCHEMBL5401398 0.73 GAA (0.42) MAPTALDH1A1GAALMNATSHR
SCHEMBL11105904 0.72 MAPT (0.44) MAPTALDH1A1NPSR1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111040450-A Low-dielectric fluorine-containing polyimide composite film and preparation method thereof 山东华夏神舟新材料有限公司 2020-04-21 CN claimed
CN-108504251-B High-viscosity corrosion-resistant water-based tile adhesive and preparation method thereof 湖南辰砾新材料有限公司 2020-01-21 CN claimed
CN-108463493-B Polymeric substrate having a surface with reduced biomolecule adhesion and thermoplastic articles of such substrate SIO2医药产品公司 2021-10-15 CN disclosed
CN-111040450-A Low-dielectric fluorine-containing polyimide composite film and preparation method thereof 山东华夏神舟新材料有限公司 2020-04-21 CN disclosed
CN-110885410-A Fluorosilicone modified acid and alkali resistant epoxy resin emulsion and preparation method thereof 湖南辰砾新材料有限公司 2020-03-17 CN disclosed
CN-108504251-B High-viscosity corrosion-resistant water-based tile adhesive and preparation method thereof 湖南辰砾新材料有限公司 2020-01-21 CN disclosed
CN-103732210-A Cosmetic compositions WACKER CHEMIE AG 2014-04-16 CN disclosed
US-8197591-B2 Pearlescent pigments having a secondary coating comprising α-silanes and method for the production thereof ECKART GMBH (DE) 2012-06-12 US disclosed
EP-1904587-B8 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING (ALPHA)-SILANES AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2011-05-25 EP disclosed
EP-1904587-B1 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING -SILANES AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2010-11-03 EP disclosed
US-20090249979-A1 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING ALPHA-SILANES AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2009-10-08 US disclosed
EP-1904587-A2 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING -SILANES AND METHOD FOR THE PRODUCITON THEREOF Eckart GmbH (DE) 2008-04-02 EP disclosed
WO-2008015123-A1 PREPARATION OF ACID DERIVATIVE-FUNCTIONAL ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2008-02-07 WO disclosed
US-7276615-B2 Organofunctional surface-modified metal oxides WACKER CHEMIE AG (DE) 2007-10-02 US disclosed
WO-2007098887-A2 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING α-SILANES AND METHOD FOR THE PRODUCITON THEREOF ECKART GMBH (DE) 2007-09-07 WO disclosed
EP-1473296-B1 Organofunctional surface modified metal oxides WACKER CHEMIE AG (DE) 2006-08-02 EP disclosed
US-20040220419-A1 Organofunctional surface-modified metal oxides WACKER-CHEMIE GMBH (DE) 2004-11-04 US disclosed
EP-1473296-A1 Organofunctional surface modified metal oxides Wacker-Chemie GmbH (DE) 2004-11-03 EP disclosed
EP-0776930-A1 Process for reclamation of recycled polyolefins and polymeric material manufactured according to this process Pheniplastics S.A. (LI) 1997-06-04 EP disclosed