SCHEMBL980165

SCHEMBL980165

CO[SiH](CNc1ccccc1)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.43
ALDH1A1 P00352 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
RAB9A P51151 2/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
CA2 P00918 2/20 0.36
KCNH3 Q9ULD8 1/20 0.36
CA1 P00915 1/20 0.36
TAS2R38 P59533 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HTT P42858 1/20 0.35
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1854492 0.79 MAPT (0.40) MAPTALDH1A1L3MBTL1TSHRMEN1
SCHEMBL140668 0.79 MAPT (0.50) MAPTALDH1A1L3MBTL1TSHRMEN1
SCHEMBL1857812 0.76 HPGD (0.42) MAPTALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL15063443 0.76 MAPT (0.57) MAPTALDH1A1L3MBTL1LMNACYP1A2
SCHEMBL49468 0.75 MAPT (0.55) MAPTALDH1A1L3MBTL1LMNACYP1A2
SCHEMBL25403652 0.74 MAPT (0.53) MAPTALDH1A1L3MBTL1KCNH3
SCHEMBL15361090 0.74 MAPT (0.53) MAPTALDH1A1L3MBTL1KCNH3
SCHEMBL5401398 0.72 GAA (0.42) MAPTALDH1A1TSHRMEN1KMT2A
SCHEMBL11105904 0.71 MAPT (0.44) MAPTALDH1A1L3MBTL1TSHRMEN1
SCHEMBL15135124 0.71 MEN1 (0.50) MAPTALDH1A1MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115542667-A Solvent-free negative photoresist with high resolution and preparation method thereof 万华化学集团股份有限公司 2022-12-30 CN claimed
CN-103436926-A Method for codeposition of silane coupling agent and metal nickel ions UNIV SHENYANG LIGONG 2013-12-11 CN claimed
CN-103215630-A Method for sealing aluminum alloy anode oxide film pore by adopting organic-inorganic composite silica sol UNIV SHENYANG LIGONG 2013-07-24 CN claimed
EP-2350178-B2 METHOD FOR PRODUCING A FLAME RETARDANT FOAM FORMING COMPOSITION SOUDAL (BE) 2025-04-23 EP disclosed
EP-2909410-B1 IMPROVED WINDOW INSULATION SOUDAL (BE) 2023-09-27 EP disclosed
CN-115542667-A Solvent-free negative photoresist with high resolution and preparation method thereof 万华化学集团股份有限公司 2022-12-30 CN disclosed
CN-115368873-A Method for producing polishing composition 福吉米株式会社 2022-11-22 CN disclosed
CN-108463493-B Polymeric substrate having a surface with reduced biomolecule adhesion and thermoplastic articles of such substrate SIO2医药产品公司 2021-10-15 CN disclosed
CN-107922592-B Aqueous adhesive compositions based on epoxy resins with improved adhesion promotion and storage stability SIKA技术股份公司 2021-08-10 CN disclosed
CN-109400870-B Modified polyether resin and preparation method and application thereof 湖南柯盛新材料有限公司 2020-09-08 CN disclosed
EP-2350178-B1 METHOD FOR PRODUCING A FLAME RETARDANT FOAM FORMING COMPOSITION SOUDAL (BE) 2018-11-28 EP disclosed
CN-103215630-A Method for sealing aluminum alloy anode oxide film pore by adopting organic-inorganic composite silica sol UNIV SHENYANG LIGONG 2013-07-24 CN disclosed
EP-2350178-A2 PRESSURISED CONTAINER CONTAINING A FLAME RETARDANT FOAM FORMING COMPOSITION AND METHOD FOR ITS PRODUCTION Soudal (BE) 2011-08-03 EP disclosed
US-7875658-B2 Isocyanate-free prepolymer mixtures for producing noncracking spray foams and have improved fireproofing; a foamable polyetherurethane based on halogenated polyethers having alkoxysilane end groups and a blowing agent; shrinkage inhibition;nontoxic insulation; construction materials; seals WACKER CHEMIE AG (DE) 2011-01-25 US disclosed
WO-2010058036-A2 PRESSURISED CONTAINER CONTAINING A FLAME RETARDANT FOAM FORMING COMPOSITION AND METHOD FOR ITS PRODUCTION SOUDAL (BE) 2010-05-27 WO disclosed
US-20060148921-A1 Expansible mixtures devoid of isocyanates exhibiting improved fire behaviour WACKER CHEMIE AG (DE) 2006-07-06 US disclosed
EP-1613691-B1 EXPANSIBLE MIXTURES DEVOID OF ISOCYANATES EXHIBITING IMPROVED FIRE BEHAVIOUR CONSORTIUM ELEKTROCHEM IND (DE) 2006-06-28 EP disclosed
EP-1106661-B1 Coating composition and hardened film obtained therefrom JSR CORP (JP) 2006-03-08 EP disclosed
US-6660394-B1 Siloxane-vinyl copolymer, oxazoline crosslinker and organo-metallic betaketone or multifunctional hydrazine; rapid low temperature curing; water, weather, chemical, acid, alkali and wear resistance; durable adhesion JSR CORPORATION (JP) 2003-12-09 US disclosed
EP-1106661-A2 Coating composition and hardened film obtained therefrom JSR Corporation (JP) 2001-06-13 EP disclosed