SCHEMBL483772

SCHEMBL483772

CCO[SiH](CCCNc1ccccc1)OCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
MAPT P10636 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.39
KCNH3 Q9ULD8 3/20 0.37
NPSR1 Q6W5P4 1/20 0.36
PPARG P37231 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
ALOX15 P16050 1/20 0.33
HTT P42858 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL722359 0.95 ALDH1A1 (0.52) ALDH1A1MAPTL3MBTL1KCNH3NPSR1
SCHEMBL25403135 0.93 ALDH1A1 (0.50) ALDH1A1MAPTL3MBTL1KCNH3NPSR1
SCHEMBL15360416 0.93 ALDH1A1 (0.50) ALDH1A1MAPTL3MBTL1KCNH3NPSR1
SCHEMBL774108 0.89 MAPT (0.47) ALDH1A1MAPTL3MBTL1KCNH3NPSR1
SCHEMBL1136014 0.87 MAPT (0.50) ALDH1A1MAPTL3MBTL1KCNH3PPARG
SCHEMBL15063443 0.82 MAPT (0.57) ALDH1A1MAPTL3MBTL1KCNH3PPARG
SCHEMBL1854492 0.78 MAPT (0.40) ALDH1A1MAPTL3MBTL1NPSR1CYP1A2
SCHEMBL3260846 0.78 GAA (0.56) ALDH1A1MAPTL3MBTL1NPSR1PPARG
SCHEMBL49468 0.77 MAPT (0.55) ALDH1A1MAPTL3MBTL1KCNH3PPARG
SCHEMBL3921217 0.77 MAOA (0.55) MAPTBCHEGAAKDM4EHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12580110-B2 Superconducting coil, superconducting device, and liquid epoxy resin composition KABUSHIKI KAISHA TOSHIBA (JP) 2026-03-17 US claimed
US-20230298791-A1 SUPERCONDUCTING COIL, SUPERCONDUCTING DEVICE, AND LIQUID EPOXY RESIN COMPOSITION KABUSHIKI KAISHA TOSHIBA (JP) 2023-09-21 US claimed
US-12580110-B2 Superconducting coil, superconducting device, and liquid epoxy resin composition KABUSHIKI KAISHA TOSHIBA (JP) 2026-03-17 US disclosed
US-20260048880-A1 HIGH EFFICIENCY PHARMACEUTICAL FILLING LINE CORNING INC (US) 2026-02-19 US disclosed
EP-3959180-B1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYSILAZANE CORNING INC (US) 2025-10-15 EP disclosed
US-12409103-B2 Glass articles with low-friction coatings CORNING INCORPORATED (US) 2025-09-09 US disclosed
US-12391600-B2 Delamination resistant glass containers with heat-tolerant coatings CORNING INCORPORATED (US) 2025-08-19 US disclosed
US-12365498-B2 High efficiency pharmaceutical filling line CORNING INCORPORATED (US) 2025-07-22 US disclosed
US-20250109324-A1 CURING AGENT FOR EPOXY RESIN, AND ADHESIVE SUNSTAR ENGINEERING INC. (JP) 2025-04-03 US disclosed
EP-4444665-A1 CHEMICALLY DURABLE BOROSILICATE GLASS COMPOSITIONS FOR STORING PHARMACEUTICAL COMPOSITIONS AND ARTICLES FORMED THEREFROM Corning Incorporated (US) 2024-10-16 EP disclosed
CN-118541334-A Chemically durable borosilicate glass compositions for storage of pharmaceutical compositions and articles formed therefrom 康宁股份有限公司 2024-08-23 CN disclosed
EP-2660244-A1 Organoxysilane compounds having silyl-protected secondary amino group and making method Shin-Etsu Chemical Co., Ltd. (JP) 2013-11-06 EP disclosed
WO-2013130724-A2 GLASS ARTICLES WITH LOW-FRICTION COATINGS CORNING INCORPORATED (US) 2013-09-06 WO disclosed
US-20130224407-A1 Glass Articles With Low-Friction Coatings CORNING INCORPORATED (US) 2013-08-29 US disclosed
US-20130171456-A1 Glass Articles With Low-Friction Coatings CORNING INCORPORATED (US) 2013-07-04 US disclosed
US-20120034670-A1 ORGANIC-INORGANIC COMPOSITE MATERIAL AND PROCESS FOR PRODUCING SAME NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) 2012-02-09 US disclosed
EP-2412677-A1 ORGANIC-INORGANIC COMPOSITE MATERIAL AND PROCESS FOR PRODUCING SAME National University Corporation Okayama University (JP) 2012-02-01 EP disclosed
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120034670-A1 ORGANIC-INORGANIC COMPOSITE MATERIAL AND PROCESS FOR PRODUCING SAME RIOX2, MAOA, FTO ALDH1A1 842/4885MAPT 3786/4885L3MBTL1 4830/4885
US-20260048880-A1 HIGH EFFICIENCY PHARMACEUTICAL FILLING LINE HTR2B, P2RY10, P2RX4 ALDH1A1 3630/4885MAPT 1515/4885L3MBTL1 4696/4885
US-12580110-B2 Superconducting coil, superconducting device, and liquid epoxy resin composition CTCF, TPR, POT1 ALDH1A1 4644/4885MAPT 2375/4885L3MBTL1 1015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.