Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19361126 | 1.00 | STAT3 (0.46) | STAT3ACHEALBFFAR1TSHR | |
| SCHEMBL7612976 | 0.84 | FFAR1 (0.59) | STAT3ACHEFFAR1TSHRACACB | |
| SCHEMBL10241629 | 0.82 | ESR1 (0.53) | STAT3ACHEFFAR1TSHRALDH1A1 | |
| SCHEMBL14731823 | 0.82 | ACHE (0.67) | STAT3ACHEFFAR1TSHRALDH1A1 | |
| SCHEMBL6046252 | 0.79 | MAPT (0.45) | STAT3ACHEFFAR1TSHRACACB | |
| SCHEMBL1149358 | 0.79 | FFAR1 (0.53) | FFAR1ALDH1A1CYP3A4HPGDCYP2C19 | |
| SCHEMBL1149769 | 0.79 | FFAR1 (0.53) | FFAR1ALDH1A1CYP3A4HPGDCYP2C19 | |
| SCHEMBL11484603 | 0.79 | FFAR1 (0.53) | FFAR1ALDH1A1CYP3A4HPGDCYP2C19 | |
| SCHEMBL3647766 | 0.78 | GSK3B (0.42) | STAT3ALBACACBALDH1A1TDP1 | |
| SCHEMBL11477030 | 0.78 | GRIA4 (0.49) | STAT3ACHEFFAR1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349554-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | COGNITION THERAPEUTICS, INC. | 2017-12-07 | — | — | US | disclosed |
| US-20170049723-A1 | ISOLATED COMPOUNDS FROM TURMERIC OIL AND METHODS OF USE | COGNITION THERAPEUTICS, INC. | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349554-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | TMEM97, SLC18A2, SIGMAR1 | STAT3 4728/4885ACHE 398/4885ALB 4181/4885 |
| US-20170049723-A1 | ISOLATED COMPOUNDS FROM TURMERIC OIL AND METHODS OF USE | APP, MAPT, PSEN1 | STAT3 284/4885ACHE 6/4885ALB 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.