Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17875268 | 0.84 | ACHE (0.61) | MAPTRAB9AACHEALDH1A1HTT | |
| SCHEMBL14567176 | 0.84 | ESR1 (0.48) | MAPTRAB9AACHEALDH1A1HTT | |
| SCHEMBL2881396 | 0.84 | ESR1 (0.48) | MAPTRAB9AACHEALDH1A1HTT | |
| SCHEMBL13140497 | 0.84 | ESR1 (0.48) | MAPTRAB9AACHEALDH1A1HTT | |
| SCHEMBL17754960 | 0.84 | RAB9A (0.51) | MAPTRAB9AACACBALDH1A1HTT | |
| SCHEMBL31615146 | 0.83 | ALDH1A1 (0.44) | MAPTACHEALDH1A1HTTFFAR1 | |
| SCHEMBL12744760 | 0.82 | ALDH1A1 (0.59) | MAPTRAB9AACHEALDH1A1HTT | |
| SCHEMBL12268175 | 0.82 | ALDH1A1 (0.59) | MAPTRAB9AACHEALDH1A1HTT | |
| SCHEMBL502093 | 0.82 | ALDH1A1 (0.49) | MAPTRAB9AACHEALDH1A1HTT | |
| SCHEMBL17451233 | 0.82 | ALDH1A1 (0.59) | MAPTRAB9AACHEALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060159681-A1 | Compositions and methods to inhibit cell loss by using inhibitors of BAG | FUNCTIONAL NEUROSCIENCE INC. (CA) | 2006-07-20 | — | — | US | disclosed |