Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.69 |
| ▸ | MEN1 | O00255 | 10/20 | 0.69 |
| ▸ | CTDSP1 | Q9GZU7 | 5/20 | 0.69 |
| ▸ | BLM | P54132 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.58 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.58 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.58 |
| ▸ | DDX3X | O00571 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.55 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12008606 | 0.87 | PTPN12 (0.76) | KMT2AMEN1CTDSP1BLMNPC1 | |
| SCHEMBL18545509 | 0.86 | KMT2A (0.78) | KMT2AMEN1CTDSP1BLMNPC1 | |
| SCHEMBL12008607 | 0.85 | KMT2A (0.75) | KMT2AMEN1CTDSP1BLMNPC1 | |
| SCHEMBL17319563 | 0.82 | KMT2A (0.83) | KMT2AMEN1CTDSP1BLMNPC1 | |
| SCHEMBL17319553 | 0.82 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMNPC1 | |
| SCHEMBL12008605 | 0.82 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMNPC1 | |
| SCHEMBL12008604 | 0.80 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMNPC1 | |
| SCHEMBL17319549 | 0.80 | KMT2A (1.00) | KMT2AMEN1CTDSP1BLMNPC1 | |
| SCHEMBL12008726 | 0.78 | PTPN12 (0.90) | KMT2AMEN1NPC1GPR35PTPN12 | |
| SCHEMBL12008563 | 0.78 | GPR35 (0.76) | KMT2AMEN1CTDSP1BLMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170049751-A1 | OXAZOLE AND THIAZOLE COMPOUNDS AS BETA-CATENIN MODULATORS AND USES THEREOF | DASGUPTA RAMANUJ (US) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170049751-A1 | OXAZOLE AND THIAZOLE COMPOUNDS AS BETA-CATENIN MODULATORS AND USES THEREOF | CTNNB1, CTNNA1, CTNNBL1 | KMT2A 4591/4885MEN1 4655/4885CTDSP1 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.