Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 8/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291157 | 0.86 | KMT2A (0.44) | KMT2ACCR2SSTR4SSTR1DRD2 | |
| SCHEMBL17327907 | 0.85 | KMT2A (0.42) | KMT2ADRD2HTR2ADRD3HTR1A | |
| SCHEMBL18291124 | 0.85 | KMT2A (0.42) | KMT2ACCR2SSTR4SSTR1KDM5A | |
| SCHEMBL18546663 | 0.85 | KMT2A (0.42) | KMT2ACCR2SSTR4SSTR1KDM5A | |
| SCHEMBL8464549 | 0.84 | KMT2A (0.53) | KMT2ATSHRDRD2HTR2ADRD3 | |
| SCHEMBL18909746 | 0.82 | CCR2 (0.49) | CCR2SSTR4SSTR1KDM5A | |
| SCHEMBL15112953 | 0.78 | KMT2A (0.47) | KMT2ATSHRDRD2HTR2ADRD3 | |
| SCHEMBL11709328 | 0.78 | EPHX1 (0.47) | KMT2ASMN1; SMN2 | |
| SCHEMBL11709334 | 0.78 | EPHX1 (0.47) | KMT2ASMN1; SMN2 | |
| SCHEMBL13647683 | 0.78 | KMT2A (0.47) | KMT2ALMNATHRBALOX12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170049109-A1 | ANTIMICROBIAL POLYMERIC COMPOSITIONS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170049109-A1 | ANTIMICROBIAL POLYMERIC COMPOSITIONS | SLC11A2, ARG1, NGLY1 | KMT2A 4508/4885CCR2 1157/4885SSTR4 3653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.