Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.95 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.95 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzo[D]Thiazole SCHEMBL27404988 | 0.98 | ALDH1A1 (0.91) | ALDH1A1HSD17B10NPC1RAB9ATDP1 | |
| Benzo[D]Thiazole SCHEMBL27741535 | 0.98 | ALDH1A1 (0.91) | ALDH1A1HSD17B10NPC1RAB9ATDP1 | |
| Benzo[D]Thiazole SCHEMBL10847268 | 0.97 | — | — | |
| Benzo[D]Thiazole SCHEMBL8430 | 0.97 | — | — | |
| Benzo[D]Thiazole SCHEMBL31388426 | 0.97 | — | — | |
| Benzo[D]Thiazole SCHEMBL900814 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HSD17B10NPC1RAB9ATDP1 | |
| Benzo[D]Thiazole SCHEMBL451685 | 0.97 | — | — | |
| Benzo[D]Thiazole SCHEMBL9815307 | 0.95 | ALDH1A1 (0.86) | ALDH1A1HSD17B10NPC1RAB9ATDP1 | |
| Benzo[D]Thiazole SCHEMBL9551908 | 0.95 | ALDH1A1 (0.95) | ALDH1A1HSD17B10NPC1RAB9ATDP1 | |
| Benzo[D]Thiazole SCHEMBL5141991 | 0.95 | ALDH1A1 (0.95) | ALDH1A1HSD17B10NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11173146-B2 | Selective activators of the intermediate conductance CA2+activated K+ channel KCa3.1 and their methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-16 | — | — | US | disclosed |
| CN-109839359-A | One kind is for detecting Pb2+The kit and detection method of concentration | 四川大学 | 2019-06-04 | — | — | CN | disclosed |
| CN-109511264-A | Polymethine compound | 株式会社艾迪科 | 2019-03-22 | — | — | CN | disclosed |
| CN-109100313-A | A kind of kit for detecting Pb ion and Ni ion, detection method and its method for measurement of concentration | 四川大学 | 2018-12-28 | — | — | CN | disclosed |
| CN-109100339-A | A kind of kit and detection method for selective enumeration method Pb ion and Ag ion concentration | 四川大学 | 2018-12-28 | — | — | CN | disclosed |
| CN-108301002-A | A kind of steel corrosion inhibiter and preparation method thereof | 苏州科技大学 | 2018-07-20 | — | — | CN | disclosed |
| CN-107915693-A | The method that the thio formyl chloride of N under a kind of microwave radiation, N dimethylamino catalyzes and synthesizes 2 amino-benzothiazole derivatives | 福建医科大学 | 2018-04-17 | — | — | CN | disclosed |
| CN-104379117-B | The method for being used for keratin fiber and being dyed including dyes/pigments, light-sensitive compound and light source | 莱雅公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-107001808-A | Part cyanine compound | 株式会社艾迪科 | 2017-08-01 | — | — | CN | disclosed |
| US-20170056376-A1 | SELECTIVE ACTIVATORS OF THE INTERMEDIATE CONDUCTANCE CA2+ACTIVATED K+ CHANNEL KCa3.1 AND THEIR METHODS OF USE | UNIV CALIFORNIA (US) | 2017-03-02 | — | — | US | disclosed |
| CN-104379117-A | Process for dyeing keratin fibres comprising a dye/pigment, a photoactive compound and a light source | OREAL | 2015-02-25 | — | — | CN | disclosed |
| CN-102015909-B | Color correction material, film-forming composition, and optical filter | ADEKA CORP | 2014-04-09 | — | — | CN | disclosed |
| CN-101863855-B | Preparation of temperature sensitive acidic ionic liquid and method of using the same in catalyzing alcoholic acid esterification | UNIV SICHUAN | 2013-05-29 | — | — | CN | disclosed |
| CN-102575107-A | Color tone correction agent, squarylium salt compound, and optical filter | ADEKA CORP | 2012-07-11 | — | — | CN | disclosed |
| CN-101529282-B | Light filter | ADEKA CORP | 2011-05-18 | — | — | CN | disclosed |
| CN-102015909-A | Color correction material, film-forming composition, and optical filter | ADEKA CORP | 2011-04-13 | — | — | CN | disclosed |
| CN-101863855-A | Preparation of temperature sensitive acidic ionic liquid and method of using the same in catalyzing alcoholic acid esterification | UNIV SICHUAN | 2010-10-20 | — | — | CN | disclosed |
| CN-101008688-B | Optical filter | ADEKA CORP | 2010-09-08 | — | — | CN | disclosed |
| CN-101529282-A | Light filter | ADEKA CORP (JP) | 2009-09-09 | — | — | CN | disclosed |
| CN-101008688-A | Optical filter | ADEKA CORP (JP) | 2007-08-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11173146-B2 | Selective activators of the intermediate conductance CA2+activated K+ channel KCa3.1 and their methods of use | KCNN3, KCNN1, KCNN2 | ALDH1A1 3038/4885HSD17B10 4181/4885NPC1 2863/4885 |
| US-20170056376-A1 | SELECTIVE ACTIVATORS OF THE INTERMEDIATE CONDUCTANCE CA2+ACTIVATED K+ CHANNEL KCa3.1 AND THEIR METHODS OF USE | KCNN3, KCNN1, KCNN2 | ALDH1A1 3038/4885HSD17B10 4181/4885NPC1 2863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.