Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22704314 | 0.81 | MEN1 (0.48) | — | |
| SCHEMBL18540817 | 0.80 | KDR (0.42) | — | |
| SCHEMBL17485887 | 0.72 | SIGMAR1 (0.51) | SIGMAR1 | |
| SCHEMBL19033038 | 0.70 | KDR (0.56) | — | |
| SCHEMBL18540823 | 0.70 | KDR (0.56) | — | |
| SCHEMBL22699501 | 0.68 | ADORA1 (0.34) | — | |
| SCHEMBL17374722 | 0.67 | SIGMAR1 (0.54) | SIGMAR1 | |
| SCHEMBL25922215 | 0.67 | SIGMAR1 (0.50) | SIGMAR1 | |
| SCHEMBL10130332 | 0.65 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL129446 | 0.65 | SIGMAR1 (0.51) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017031176-A1 | MONOCYCLIC, THIENO, PYRIDO, AND PYRROLO PYRIMIDINE COMPOUNDS AND METHODS OF USE AND MANUFACTURE OF THE SAME | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2017-02-23 | — | — | WO | disclosed |