Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 17/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30966769 | 1.00 | SIGMAR1 (0.51) | SIGMAR1ALDH1A1TSHRHDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL2867283 | 0.98 | SIGMAR1 (0.53) | SIGMAR1ALDH1A1TSHRHDAC1HDAC6 | |
| SCHEMBL10908956 | 0.89 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL6739011 | 0.88 | FYN (0.49) | SIGMAR1ALDH1A1TSHR | |
| SCHEMBL17485887 | 0.86 | SIGMAR1 (0.51) | SIGMAR1TSHR | |
| SCHEMBL25922215 | 0.84 | SIGMAR1 (0.50) | SIGMAR1TSHR | |
| SCHEMBL11861528 | 0.84 | HDAC1 (0.60) | ALDH1A1TSHRHDAC1HDAC6KMT2A | |
| SCHEMBL10130332 | 0.83 | SIGMAR1 (0.53) | SIGMAR1TSHRKMT2A | |
| SCHEMBL18499750 | 0.83 | SIGMAR1 (0.53) | SIGMAR1TSHR | |
| SCHEMBL169805 | 0.83 | ALDH1A1 (0.47) | SIGMAR1ALDH1A1TSHRHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184520-A | Biphenyl amine compound, preparation method thereof and application thereof in flow battery | 中国科学院大连化学物理研究所 | 2024-06-14 | — | — | CN | claimed |
| CN-118184520-A | Biphenyl amine compound, preparation method thereof and application thereof in flow battery | 中国科学院大连化学物理研究所 | 2024-06-14 | — | — | CN | disclosed |
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
| US-20230242535-A1 | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | BRISTOL MYERS SQUIBB CO (US) | 2023-08-03 | — | — | US | disclosed |
| US-20210309647-A1 | Apoptosis Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-10-07 | — | — | US | disclosed |
| US-11116772-B2 | Medical methods utilising high purity diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2021-09-14 | — | — | US | disclosed |
| US-11116772-B2 | Medical methods utilising high purity diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2021-09-14 | — | — | US | disclosed |
| US-11034680-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-06-15 | — | — | US | disclosed |
| US-20210052514-A1 | IMMUNOMODULATOR COMPOUNDS | CHEMOCENTRYX, INC. | 2021-02-25 | — | — | US | disclosed |
| EP-0145400-A2 | Photoconductive devices containing novel squaraine compounds | XEROX CORPORATION (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4524219-A | REACTING AN ALKYL AQUARATE WITH AN N,N-DIALKYLANILINE IN THE PRESENCE OF AN ALKANOL | XEROX CORPORATION (US) | 1985-06-18 | — | — | US | disclosed |
| US-4524220-A | REACTING SQUARIC ACID AND AN AROMATIC DIAMINE; PHOTOSTABILITY | XEROX CORPORATION (US) | 1985-06-18 | — | — | US | disclosed |
| EP-0144206-A2 | Process for synthesising squaraine compositions | XEROX CORPORATION (US) | 1985-06-12 | — | — | EP | disclosed |
| US-4523035-A | BLUE AND GREEN PIGMENTS | XEROX CORPORATION (US) | 1985-06-11 | — | — | US | disclosed |
| US-4486520-A | Photoconductive devices containing novel squaraine compositions | XEROX CORPORATION (US) | 1984-12-04 | — | — | US | disclosed |
| US-4459186-A | Electrochemical oxidation of alkyl aromatic compounds | UOP INC. (US) | 1984-07-10 | — | — | US | disclosed |
| EP-0042357-B1 | AZO DYES, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1984-06-06 | — | — | EP | disclosed |
| EP-0042357-A2 | Azo dyes, their preparation and use | CIBA-GEIGY AG (CH) | 1981-12-23 | — | — | EP | disclosed |
| US-4251629-A | COLORIMETRY, USING 4-AMINOANTIPYRENE, N-SUBSTITUTED ANILINE, ACTIVATOR | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1981-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11116772-B2 | Medical methods utilising high purity diaminophenothiazinium compounds | MGMT, MAPT, TST | SIGMAR1 3875/4885ALDH1A1 3409/4885TSHR 1274/4885 |
| US-11725000-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | SIGMAR1 4698/4885ALDH1A1 550/4885TSHR 4738/4885 |
| US-20230242535-A1 | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | F2RL3, F2R, TMPRSS4 | SIGMAR1 683/4885ALDH1A1 2611/4885TSHR 128/4885 |
| US-20210052514-A1 | IMMUNOMODULATOR COMPOUNDS | IL2, IL2RA, C3AR1 | SIGMAR1 1100/4885ALDH1A1 1113/4885TSHR 320/4885 |
| US-11034680-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | SIGMAR1 4698/4885ALDH1A1 550/4885TSHR 4738/4885 |
| US-20210309647-A1 | Apoptosis Inhibitors | BAX, SDHA, SDHB | SIGMAR1 4698/4885ALDH1A1 550/4885TSHR 4738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.