SCHEMBL185520

SCHEMBL185520

Nc1ccc(F)cc1C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
FFAR4 Q5NUL3 8/20 0.51
IDO1 P14902 2/20 0.50
KEAP1 Q14145 1/20 0.42
GLA P06280 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
KIF11 P52732 1/20 0.39
FFAR1 O14842 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8996706 0.98 IDO1 (0.52) ALDH1A1FFAR4IDO1KEAP1GLA
Hydrochloric Acid SCHEMBL4372850 0.98 IDO1 (0.52) ALDH1A1FFAR4IDO1KEAP1GLA
SCHEMBL24244880 0.82 ALDH1A1 (0.48) ALDH1A1FFAR4IDO1KEAP1GLA
SCHEMBL186087 0.81 KIF11 (0.48) ALDH1A1FFAR4IDO1KEAP1GLA
SCHEMBL29978561 0.81 KIF11 (0.48) ALDH1A1FFAR4IDO1KEAP1GLA
SCHEMBL279009 0.79 ALDH1A1 (0.50) ALDH1A1FFAR4IDO1KEAP1GAA
SCHEMBL21332700 0.78 SCN9A (0.47) ALDH1A1FFAR4IDO1GAASMN1; SMN2
SCHEMBL29972896 0.78 FFAR4 (0.61) ALDH1A1FFAR4IDO1FFAR1
SCHEMBL29403371 0.78 KIF11 (0.50) ALDH1A1FFAR4GLAPOLBGAA
SCHEMBL349356 0.78 KIF11 (0.50) ALDH1A1FFAR4GLAPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119592176-A Quick-drying corrosion-resistant finish paint and preparation process thereof 江苏安特克新材料研究院有限公司 2025-03-11 CN claimed
EP-1773768-B1 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2018-08-22 EP claimed
EP-1377579-B1 ACYL AND SULFONYL DERIVATIVES OF 6,9-DISUBSTITUTED 2-(TRANS-1,4-DIAMINOCYCLOHEXYL)-PURINES AND THEIR USE AS ANTIPROLIFERATIVE AGENTS AVENTIS PHARMA INC (US) 2009-03-25 EP claimed
EP-1773768-A4 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2008-08-06 EP claimed
EP-1524261-B1 Process for preparing fluorinated anilines SALTIGO GMBH (DE) 2008-06-11 EP claimed
EP-1773768-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS Exelixis, Inc. (US) 2007-04-18 EP claimed
US-7154006-B2 Preparation of fluorinated anilines BAYER AKTIENGESELLSCHAFT (DE) 2006-12-26 US claimed
WO-2006012642-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS, INC. (US) 2006-02-02 WO claimed
US-20050101795-A1 Preparation of fluorinated anilines BAYER CHEMICALS AG 2005-05-12 US claimed
EP-1524261-A1 Process for preparing fluorinated anilines Bayer Chemicals AG (DE) 2005-04-20 EP claimed
US-6861524-B2 Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents AVENTIS PHARMACEUTICALS INC. (US) 2005-03-01 US claimed
EP-1377579-A2 ACYL AND SULFONYL DERIVATIVES OF 6,9-DISUBSTITUTED 2-(TRANS-1,4-DIAMINOCYCLOHEXYL)-PURINES AND THEIR USE AS ANTIPROLIFERATIVE AGENTS Aventis Pharmaceuticals Inc. (US) 2004-01-07 EP claimed
US-20030069259-A1 Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents AVENTISUB LLC 2003-04-10 US claimed
WO-2002042303-A2 ACYL AND SULFONYL DERIVATIVES OF 6,9-DISUBSTITUTED 2-(TRANS-1,4-DIAMINOCYCLOHEXYL)-PURINES AND THEIR USE AS ANTIPROLIFERATIVE AGENTS AVENTIS PHARMACEUTICALS INC. (US) 2002-05-30 WO claimed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US claimed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed
EP-4714953-A1 MELANOCORTIN 2-TYPE RECEPTOR ANTAGONIST Scohia Pharma, Inc. (JP) 2026-03-25 EP disclosed
EP-0174131-A2 Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them FISONS plc (GB) 1986-03-12 EP disclosed
US-4145364-A PREPARATION OF FLUORINATED ANILINES MERCK & CO., INC. (US) 1979-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050101795-A1 Preparation of fluorinated anilines FLNA, FLNB, FLI1 ALDH1A1 559/4885FFAR4 591/4885IDO1 721/4885
US-20030069259-A1 Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents BAD, BAX, MCL1 ALDH1A1 1022/4885FFAR4 437/4885IDO1 3004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.