Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17356365 | 0.74 | EGFR (0.38) | EGFR | |
| SCHEMBL14148803 | 0.74 | EGFR (0.40) | EGFR | |
| SCHEMBL6606363 | 0.70 | BACE1 (0.43) | — | |
| SCHEMBL13158792 | 0.70 | BACE1 (0.43) | — | |
| SCHEMBL14148735 | 0.68 | EGFR (0.43) | EGFR | |
| SCHEMBL4731185 | 0.68 | EGFR (0.45) | EGFR | |
| SCHEMBL1206636 | 0.66 | CA12 (0.38) | — | |
| SCHEMBL21639487 | 0.66 | ALOX15 (0.38) | — | |
| SCHEMBL3178345 | 0.66 | PPARG (0.40) | — | |
| SCHEMBL5462778 | 0.66 | USP14 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580553-B2 | Thermally-activated self-immolative materials | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-02-28 | — | — | US | disclosed |