Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 11/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13829952 | 0.87 | CMA1 (0.47) | CMA1ACEELANERENF2 | |
| SCHEMBL16012277 | 0.86 | ATM (0.35) | CMA1ACEELANEITGB3ITGA2B | |
| SCHEMBL16012278 | 0.86 | ATM (0.35) | CMA1ACEELANEITGB3ITGA2B | |
| SCHEMBL8225015 | 0.83 | ACE (0.49) | CMA1ACEITGB3ITGA2BREN | |
| SCHEMBL17364182 | 0.81 | ALDH1A1 (0.33) | RENKLK5 | |
| SCHEMBL16012027 | 0.81 | ALDH1A1 (0.33) | RENKLK5 | |
| SCHEMBL16011828 | 0.80 | MEN1 (0.37) | REN | |
| SCHEMBL16011925 | 0.80 | MEN1 (0.37) | REN | |
| SCHEMBL13830148 | 0.79 | CMA1 (0.46) | CMA1ACEELANERENF2 | |
| SCHEMBL8005012 | 0.77 | ITGB3 (0.45) | CMA1ACEITGB3ITGA2BKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580463-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-02-28 | — | — | US | disclosed |