Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18557996 | 0.93 | ABCB1 (0.36) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL19309266 | 0.91 | KMT2A (0.36) | KMT2AMEN1LMNATTRADORA3 | |
| SCHEMBL19309257 | 0.83 | ITGB3 (0.36) | KMT2AMEN1LMNATTRADORA3 | |
| SCHEMBL12642759 | 0.81 | THRB (0.44) | KMT2AMEN1LMNATTRADORA3 | |
| SCHEMBL13952220 | 0.80 | THRB (0.47) | KMT2AMEN1LMNATTRADORA3 | |
| SCHEMBL16404797 | 0.78 | THRB (0.47) | KMT2AMEN1LMNATTRADORA3 | |
| SCHEMBL16325357 | 0.76 | THRB (0.44) | KMT2AMEN1LMNATTRADORA3 | |
| SCHEMBL15500211 | 0.75 | ITGB3 (0.40) | KMT2AMEN1LMNATTRADORA3 | |
| SCHEMBL16190066 | 0.74 | THRB (0.41) | KMT2AMEN1LMNATTRADORA3 | |
| SCHEMBL1526069 | 0.74 | THRB (0.59) | KMT2AMEN1LMNATTRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579300-B2 | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof | NANOPHARMACEUTICALS LLC (US) | 2017-02-28 | — | — | US | disclosed |