Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18558003 | 0.93 | KMT2A (0.37) | ABCB1MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL19309257 | 0.91 | ITGB3 (0.36) | MEN1KMT2AITGB3ITGA2BLMNA | |
| SCHEMBL19309266 | 0.84 | KMT2A (0.36) | MEN1KMT2AITGB3ITGA2BLMNA | |
| SCHEMBL12584374 | 0.82 | ITGB3 (0.44) | MEN1KMT2AITGB3ITGA2BLMNA | |
| SCHEMBL17612140 | 0.79 | ITGB3 (0.43) | MEN1KMT2AITGB3ITGA2BLMNA | |
| SCHEMBL6845190 | 0.75 | ITGB3 (0.44) | MEN1KMT2AITGB3ITGA2BLMNA | |
| SCHEMBL12584373 | 0.75 | ITGB3 (0.44) | MEN1KMT2AITGB3ITGA2BLMNA | |
| SCHEMBL12642759 | 0.74 | THRB (0.44) | MEN1KMT2AITGB3ITGA2BLMNA | |
| SCHEMBL13952220 | 0.73 | THRB (0.47) | MEN1KMT2AITGB3ITGA2BLMNA | |
| SCHEMBL5177770 | 0.72 | THRB (0.60) | MEN1KMT2AITGB3ITGA2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579300-B2 | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof | NANOPHARMACEUTICALS LLC (US) | 2017-02-28 | — | — | US | disclosed |