Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18558447 | 0.98 | CRHR1 (0.42) | CRHR1TRPV1RAB9AKDRFLT3 | |
| SCHEMBL18558306 | 0.91 | RAB9A (0.46) | CRHR1RAB9AKDRFLT3NPC1 | |
| SCHEMBL17089670 | 0.88 | ALDH1A1 (0.45) | CRHR1TRPV1RAB9AFLT3NPC1 | |
| SCHEMBL18558357 | 0.87 | RAB9A (0.39) | RAB9AKDRFLT3NPC1MAPT | |
| SCHEMBL18558518 | 0.85 | RAB9A (0.54) | CRHR1RAB9AKDRFLT3NPC1 | |
| SCHEMBL18558475 | 0.85 | KCNH2 (0.44) | RAB9ANPC1CCNA2CDK2CCNA1 | |
| SCHEMBL9921043 | 0.85 | STK25 (0.43) | TRPV1CCNA2CDK2CCNA1 | |
| SCHEMBL18558215 | 0.84 | CRHR1 (0.39) | CRHR1RAB9AKDRFLT3NPC1 | |
| SCHEMBL18558171 | 0.84 | RAB9A (0.40) | CRHR1RAB9AKDRFLT3NPC1 | |
| SCHEMBL18558478 | 0.83 | CRHR1 (0.39) | CRHR1TRPV1RAB9AKDRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580388-B2 | Pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2017-02-28 | — | — | US | disclosed |