Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 8/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605793 | 0.76 | NOS1 (0.43) | NOS1FBP1ELANE | |
| SCHEMBL5713389 | 0.75 | NOS1 (0.52) | NOS1FBP1ELANE | |
| SCHEMBL30613053 | 0.74 | NOS1 (0.52) | NOS1FBP1ELANE | |
| SCHEMBL25920064 | 0.73 | — | — | |
| SCHEMBL607368 | 0.73 | — | — | |
| SCHEMBL24062403 | 0.71 | — | — | |
| SCHEMBL1697851 | 0.71 | — | — | |
| SCHEMBL14385213 | 0.71 | — | — | |
| SCHEMBL24970049 | 0.70 | FBP1 (0.41) | NOS1FBP1ELANE | |
| SCHEMBL608178 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | UNIV SOUTHERN CALIFORNIA (US) | 2020-12-10 | — | — | US | disclosed |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2020-08-11 | — | — | US | disclosed |
| US-20180019413-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexes of Ir | UNIV SOUTHERN CALIFORNIA (US) | 2018-01-18 | — | — | US | disclosed |
| US-9583720-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | EML4, RCOR3, CPNE4 | NOS1 3820/4885FBP1 3955/4885ELANE 2313/4885 |
| US-20180019413-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexes of Ir | EML4, AFF4, RCOR3 | NOS1 3614/4885FBP1 3702/4885ELANE 1809/4885 |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | EML4, AFF4, RCOR3 | NOS1 3614/4885FBP1 3702/4885ELANE 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.