Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | IRS1 | P35568 | 1/20 | 0.36 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13961926 | 0.93 | GPR35 (0.65) | GPR35AKT1IRS1GAB1L3MBTL1 | |
| SCHEMBL14645853 | 0.88 | GPR35 (0.74) | GPR35AKT1IRS1GAB1L3MBTL1 | |
| SCHEMBL1593215 | 0.88 | GPR35 (0.74) | GPR35AKT1IRS1GAB1L3MBTL1 | |
| SCHEMBL14645768 | 0.88 | GPR35 (0.74) | GPR35AKT1IRS1GAB1L3MBTL1 | |
| SCHEMBL12374321 | 0.88 | GPR35 (0.74) | GPR35AKT1IRS1GAB1L3MBTL1 | |
| SCHEMBL18558706 | 0.83 | GPR35 (0.40) | GPR35PRSS1PRSS2PRSS3AKT1 | |
| SCHEMBL1157118 | 0.82 | GPR35 (0.49) | GPR35AKT1IRS1GAB1L3MBTL1 | |
| SCHEMBL1365121 | 0.82 | GPR35 (0.49) | GPR35AKT1IRS1GAB1L3MBTL1 | |
| SCHEMBL1364647 | 0.82 | GPR35 (0.49) | GPR35AKT1IRS1GAB1L3MBTL1 | |
| SCHEMBL1157064 | 0.82 | GPR35 (0.49) | GPR35AKT1IRS1GAB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580556-B2 | DPP with branched alkyl-chain or (and) fused thiophene with branched alkyl-chain and the related designing strategy to increase the molecular weight of their semi-conducting copolymers | CORNING INCORPORATED (US) | 2017-02-28 | — | — | US | disclosed |