Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | IRS1 | P35568 | 1/20 | 0.33 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18558705 | 0.83 | GPR35 (0.58) | GPR35NPSR1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1157064 | 0.81 | GPR35 (0.49) | GPR35NPSR1ALDH1A1MAPTAKT1 | |
| SCHEMBL1364647 | 0.81 | GPR35 (0.49) | GPR35NPSR1ALDH1A1MAPTAKT1 | |
| SCHEMBL1157118 | 0.81 | GPR35 (0.49) | GPR35NPSR1ALDH1A1MAPTAKT1 | |
| SCHEMBL1365121 | 0.81 | GPR35 (0.49) | GPR35NPSR1ALDH1A1MAPTAKT1 | |
| SCHEMBL13961926 | 0.76 | GPR35 (0.65) | GPR35NPSR1SMN1; SMN2MAPTAKT1 | |
| SCHEMBL1365090 | 0.76 | CES2 (0.47) | GPR35PLA2G4A | |
| SCHEMBL1364678 | 0.76 | CES2 (0.47) | GPR35PLA2G4A | |
| SCHEMBL1363701 | 0.76 | CES2 (0.47) | GPR35PLA2G4A | |
| SCHEMBL17985022 | 0.75 | GPR35 (0.59) | GPR35LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580556-B2 | DPP with branched alkyl-chain or (and) fused thiophene with branched alkyl-chain and the related designing strategy to increase the molecular weight of their semi-conducting copolymers | CORNING INCORPORATED (US) | 2017-02-28 | — | — | US | disclosed |