Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | IRS1 | P35568 | 1/20 | 0.38 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1157118 | 1.00 | GPR35 (0.49) | GPR35L3MBTL1NPSR1TSHRMAPT | |
| SCHEMBL1157064 | 1.00 | GPR35 (0.49) | GPR35L3MBTL1NPSR1TSHRMAPT | |
| SCHEMBL1365121 | 1.00 | GPR35 (0.49) | GPR35L3MBTL1NPSR1TSHRMAPT | |
| SCHEMBL13961926 | 0.88 | GPR35 (0.65) | GPR35L3MBTL1NPSR1TSHRMAPT | |
| SCHEMBL9948709 | 0.88 | GPR35 (0.49) | GPR35L3MBTL1NPSR1TSHRALDH1A1 | |
| SCHEMBL14645853 | 0.83 | GPR35 (0.74) | GPR35L3MBTL1NPSR1TSHRMAPT | |
| SCHEMBL14645768 | 0.83 | GPR35 (0.74) | GPR35L3MBTL1NPSR1TSHRMAPT | |
| SCHEMBL12374321 | 0.83 | GPR35 (0.74) | GPR35L3MBTL1NPSR1TSHRMAPT | |
| SCHEMBL1593215 | 0.83 | GPR35 (0.74) | GPR35L3MBTL1NPSR1TSHRMAPT | |
| SCHEMBL18558705 | 0.82 | GPR35 (0.58) | GPR35L3MBTL1NPSR1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571888-B1 | METHODS OF MAKING FUSED THIOPHENES | CORNING INC (US) | 2014-12-31 | — | — | EP | disclosed |
| EP-2571888-A1 | METHODS OF MAKING FUSED THIOPHENES | Corning Incorporated (US) | 2013-03-27 | — | — | EP | disclosed |
| US-8217183-B2 | Methods of making fused thiophenes | CORNING INCORPORATED (US) | 2012-07-10 | — | — | US | disclosed |
| WO-2011146308-A1 | METHODS OF MAKING FUSED THIOPHENES | CORNING INCORPORATED (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110288306-A1 | METHODS OF MAKING FUSED THIOPHENES | CORNING INCORPORATED | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288306-A1 | METHODS OF MAKING FUSED THIOPHENES | DCX, TST, GNPAT | GPR35 2757/4885L3MBTL1 3979/4885NPSR1 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.