Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | USP2 | O75604 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18558963 | 0.93 | ATM (0.63) | LMNAHTTALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL18559133 | 0.91 | MEN1 (0.62) | LMNAHTTALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL18559279 | 0.85 | LMNA (0.74) | LMNAHTTALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL18556548 | 0.84 | MAPK1 (0.70) | LMNAHTTALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL18559056 | 0.83 | LMNA (1.00) | LMNAHTTALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL13739253 | 0.82 | ALDH1A1 (0.74) | LMNAHTTALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL19566993 | 0.82 | LMNA (0.77) | LMNAHTTALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL13737637 | 0.82 | KMT2A (0.75) | LMNAHTTALDH1A1USP2RECQL | |
| SCHEMBL19549066 | 0.80 | LMNA (0.75) | LMNAHTTALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL18559116 | 0.80 | KMT2A (0.70) | LMNAHTTALDH1A1USP2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | UNIV VANDERBILT (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| US-10813355-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| US-10188105-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2019-01-29 | — | — | US | disclosed |
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | LMNA 4714/4885HTT 3745/4885ALDH1A1 3579/4885 |
| US-10813355-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | LMNA 4708/4885HTT 3893/4885ALDH1A1 3568/4885 |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | LMNA 4714/4885HTT 3745/4885ALDH1A1 3579/4885 |
| US-10188105-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | LMNA 4745/4885HTT 3893/4885ALDH1A1 3533/4885 |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | LMNA 4708/4885HTT 3893/4885ALDH1A1 3568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.