Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | THRA | P10827 | 7/20 | 0.37 |
| ▸ | THRB | P10828 | 7/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18559013 | 0.87 | THRA (0.44) | MAOBTHRATHRB | |
| SCHEMBL18559091 | 0.78 | SLC5A1 (0.46) | CTSKMAOBTHRATHRB | |
| SCHEMBL17536185 | 0.74 | BCHE (0.40) | CTSK | |
| SCHEMBL17536186 | 0.74 | BCHE (0.40) | CTSK | |
| Hydrochloric Acid SCHEMBL17536188 | 0.73 | BCHE (0.40) | CTSK | |
| Hydrochloric Acid SCHEMBL17536187 | 0.73 | BCHE (0.40) | CTSK | |
| SCHEMBL18559089 | 0.67 | MAOB (0.38) | MAOBTHRATHRB | |
| SCHEMBL13907033 | 0.65 | MAOB (0.50) | MAOBTHRATHRB | |
| SCHEMBL30448394 | 0.63 | CTSK (1.00) | CTSKMAOB | |
| SCHEMBL7188134 | 0.62 | CTSK (0.71) | CTSKMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580399-B2 | Geranyl flavonoid derivative with improved water solubility, a method for preparing the same, and a method for treating cancer using the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2017-02-28 | — | — | US | disclosed |