Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.44 |
| ▸ | THRB | P10828 | 8/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18559091 | 0.90 | SLC5A1 (0.46) | THRATHRBMAOBALDH1A1APP | |
| SCHEMBL18559012 | 0.87 | CTSK (0.46) | THRATHRBMAOB | |
| SCHEMBL18559089 | 0.72 | MAOB (0.38) | THRATHRBMAOBKDM4EALDH1A1 | |
| SCHEMBL13907033 | 0.67 | MAOB (0.50) | THRATHRBMAOBKDM4EALDH1A1 | |
| SCHEMBL16588662 | 0.67 | POLB (0.67) | ALDH1A1NPC1PKMRAB9A | |
| SCHEMBL4724887 | 0.66 | NPC1 (0.60) | ALDH1A1NPC1PKMRAB9A | |
| SCHEMBL3658652 | 0.65 | NPC1 (0.64) | ALDH1A1APPNPC1PKMRAB9A | |
| SCHEMBL11195222 | 0.65 | THRB (0.76) | THRATHRBKDM4EALDH1A1 | |
| SCHEMBL2875989 | 0.65 | KMT2A (0.69) | THRBKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL30254972 | 0.65 | KMT2A (0.69) | THRBKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580399-B2 | Geranyl flavonoid derivative with improved water solubility, a method for preparing the same, and a method for treating cancer using the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2017-02-28 | — | — | US | disclosed |