Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 15/20 | 0.55 |
| ▸ | CA1 | P00915 | 14/20 | 0.55 |
| ▸ | CA2 | P00918 | 14/20 | 0.55 |
| ▸ | CA12 | O43570 | 6/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14076112 | 0.89 | CA9 (0.68) | CA9CA1CA2CA12CA14 | |
| SCHEMBL18559017 | 0.89 | CA9 (0.60) | CA9CA1CA2CA12CA14 | |
| SCHEMBL13698023 | 0.87 | CA9 (0.60) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17067944 | 0.85 | CA9 (0.61) | CA9CA1CA2CA12CA14 | |
| SCHEMBL24943216 | 0.84 | USP2 (0.58) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14806746 | 0.83 | CA9 (0.57) | CA9CA1CA2CA12CA14 | |
| SCHEMBL16998357 | 0.83 | CA9 (0.63) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12793932 | 0.82 | CA9 (0.66) | CA9CA1CA2CA12CA14 | |
| 5-Iodoacetamidofluorescein SCHEMBL10146553 | 0.82 | CA9 (0.66) | CA9CA1CA2CA12CA14 | |
| SCHEMBL18474362 | 0.81 | CA1 (0.67) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2770053-B1 | In vivo incorporation of alkynyl amino acids into proteins in eubacteria | SCRIPPS RESEARCH INST (US) | 2018-02-21 | — | — | EP | disclosed |
| US-9797908-B2 | Unnatural reactive amino acid genetic code additions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-10-24 | — | — | US | disclosed |
| US-9797908-B2 | Unnatural reactive amino acid genetic code additions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-10-24 | — | — | US | disclosed |
| US-9580721-B2 | Expanding the eukaryotic genetic code | The Scripps Reserach Institute (US) | 2017-02-28 | — | — | US | disclosed |
| US-9580721-B2 | Expanding the eukaryotic genetic code | The Scripps Reserach Institute (US) | 2017-02-28 | — | — | US | disclosed |
| EP-2410331-B1 | Aminoacyl-tRNA synthetase for aminoacylation tRNA with unnatural amino acids | SCRIPPS RESEARCH INST (US) | 2015-09-23 | — | — | EP | disclosed |
| US-20150240249-A1 | EXPANDING THE EUKARYOTIC GENETIC CODE | SCRIPPS RESEARCH INST (US) | 2015-08-27 | — | — | US | disclosed |
| US-20150240249-A1 | EXPANDING THE EUKARYOTIC GENETIC CODE | SCRIPPS RESEARCH INST (US) | 2015-08-27 | — | — | US | disclosed |
| US-8945926-B2 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-02-03 | — | — | US | disclosed |
| US-8945926-B2 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-02-03 | — | — | US | disclosed |
| US-20080227195-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-09-18 | — | — | US | disclosed |
| US-20080220472-A1 | Orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases incorporate para-propargyloxyphenylalanine into proteins produced in E. coli | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-09-11 | — | — | US | disclosed |
| US-20080220472-A1 | Orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases incorporate para-propargyloxyphenylalanine into proteins produced in E. coli | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-09-11 | — | — | US | disclosed |
| US-20080176277-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-07-24 | — | — | US | disclosed |
| US-20080176277-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-07-24 | — | — | US | disclosed |
| US-20070178448-A1 | Selective posttranslational modification of phage-displayed polypeptides | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-08-02 | — | — | US | disclosed |
| US-20070166791-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070166791-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070154952-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070154952-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070154952-A1 | Expanding the eukaryotic genetic code | NSUN3, AARS1, TRMT1 | CA9 4064/4885CA1 4466/4885CA2 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.