Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.65 |
| ▸ | USP2 | O75604 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SLC27A1 | Q6PCB7 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18559144 | 0.79 | ALDH1A1 (1.00) | MAPTNPSR1ALDH1A1USP2KMT2A | |
| SCHEMBL11888617 | 0.79 | LMNA (0.67) | MAPTNPSR1ALDH1A1HPGDMAPK1 | |
| SCHEMBL4215730 | 0.76 | ALDH1A1 (0.71) | MAPTNPSR1ALDH1A1USP2KMT2A | |
| SCHEMBL4204332 | 0.75 | ALDH1A1 (1.00) | MAPTNPSR1ALDH1A1HPGDPOLB | |
| SCHEMBL18559346 | 0.74 | ALDH1A1 (0.80) | MAPTNPSR1ALDH1A1KMT2AHPGD | |
| SCHEMBL18559322 | 0.74 | ALDH1A1 (0.80) | MAPTNPSR1ALDH1A1KMT2AHPGD | |
| SCHEMBL4211196 | 0.74 | ALDH1A1 (0.90) | MAPTNPSR1ALDH1A1KMT2AHPGD | |
| SCHEMBL4209247 | 0.74 | ALDH1A1 (0.68) | MAPTNPSR1ALDH1A1HPGDPOLB | |
| SCHEMBL4212070 | 0.74 | ALDH1A1 (0.68) | MAPTNPSR1ALDH1A1KMT2AHPGD | |
| SCHEMBL18556607 | 0.73 | MAPT (1.00) | MAPTNPSR1ALDH1A1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | UNIV VANDERBILT (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| US-10813355-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| US-10188105-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2019-01-29 | — | — | US | disclosed |
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | MAPT 1741/4885NPSR1 41/4885ALDH1A1 3579/4885 |
| US-10813355-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | MAPT 2086/4885NPSR1 47/4885ALDH1A1 3568/4885 |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | MAPT 1741/4885NPSR1 41/4885ALDH1A1 3579/4885 |
| US-10188105-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | MAPT 2002/4885NPSR1 47/4885ALDH1A1 3533/4885 |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | MAPT 2086/4885NPSR1 47/4885ALDH1A1 3568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.