Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18559238 | 0.88 | ALDH1A1 (1.00) | CYP3A4CYP2D6CYP2C19CTDSP1ALDH1A1 | |
| SCHEMBL18559080 | 0.86 | ALDH1A1 (0.83) | CYP3A4CYP2D6CYP2C19CTDSP1ALDH1A1 | |
| SCHEMBL18558952 | 0.84 | ALDH1A1 (1.00) | CYP3A4CYP2D6CYP2C19CTDSP1ALDH1A1 | |
| SCHEMBL18559342 | 0.82 | ALDH1A1 (1.00) | CYP3A4CYP2D6CYP2C19CTDSP1ALDH1A1 | |
| SCHEMBL18559325 | 0.74 | MAPT (1.00) | CYP3A4CYP2D6CYP2C19CTDSP1ALDH1A1 | |
| SCHEMBL20682661 | 0.73 | SMN1; SMN2 (0.79) | CYP3A4CYP2D6CYP2C19CTDSP1ALDH1A1 | |
| SCHEMBL18559271 | 0.71 | LMNA (1.00) | CYP3A4CYP2D6CYP2C19CTDSP1ALDH1A1 | |
| SCHEMBL20682650 | 0.71 | LMNA (0.78) | CYP3A4CYP2D6CYP2C19CTDSP1ALDH1A1 | |
| SCHEMBL18559350 | 0.69 | ALDH1A1 (1.00) | CYP3A4CYP2C19ALDH1A1GAANPSR1 | |
| SCHEMBL18559341 | 0.69 | ATM (1.00) | CYP3A4CYP2D6CYP2C19CTDSP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | UNIV VANDERBILT (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| US-10813355-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| US-10188105-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2019-01-29 | — | — | US | disclosed |
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | CYP3A4 3922/4885CYP2D6 4699/4885CYP2C19 4555/4885 |
| US-10813355-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | CYP3A4 3964/4885CYP2D6 4715/4885CYP2C19 4613/4885 |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | CYP3A4 3922/4885CYP2D6 4699/4885CYP2C19 4555/4885 |
| US-10188105-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | CYP3A4 3737/4885CYP2D6 4672/4885CYP2C19 4505/4885 |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | CYP3A4 3964/4885CYP2D6 4715/4885CYP2C19 4613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.