Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.89 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.89 |
| ▸ | USP2 | O75604 | 3/20 | 0.89 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18559372 | 0.94 | MAPT (1.00) | MAPTALDH1A1HSD17B10USP2NPSR1 | |
| SCHEMBL18559074 | 0.86 | ALDH1A1 (1.00) | MAPTALDH1A1HSD17B10USP2NPSR1 | |
| SCHEMBL13832070 | 0.85 | ALDH1A1 (0.83) | MAPTALDH1A1HSD17B10USP2NPSR1 | |
| SCHEMBL22046603 | 0.83 | MAPT (0.79) | MAPTALDH1A1HSD17B10USP2NPSR1 | |
| SCHEMBL3889633 | 0.83 | MAPT (0.82) | MAPTALDH1A1HSD17B10USP2NPSR1 | |
| SCHEMBL15986443 | 0.83 | ALDH1A1 (0.80) | MAPTALDH1A1HSD17B10USP2NPSR1 | |
| SCHEMBL15983290 | 0.83 | MAPT (0.82) | MAPTALDH1A1HSD17B10USP2NPSR1 | |
| SCHEMBL15983276 | 0.82 | ALDH1A1 (0.79) | MAPTALDH1A1HSD17B10USP2NPSR1 | |
| SCHEMBL18559153 | 0.81 | MAPT (1.00) | MAPTALDH1A1HSD17B10USP2NPSR1 | |
| SCHEMBL15983294 | 0.81 | ALDH1A1 (0.77) | MAPTALDH1A1HSD17B10USP2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | UNIV VANDERBILT (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| US-10813355-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| US-10188105-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2019-01-29 | — | — | US | disclosed |
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | MAPT 1741/4885ALDH1A1 3579/4885HSD17B10 4582/4885 |
| US-10813355-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | MAPT 2086/4885ALDH1A1 3568/4885HSD17B10 4549/4885 |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | MAPT 1741/4885ALDH1A1 3579/4885HSD17B10 4582/4885 |
| US-10188105-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | MAPT 2002/4885ALDH1A1 3533/4885HSD17B10 4480/4885 |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | MAPT 2086/4885ALDH1A1 3568/4885HSD17B10 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.