Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 3/20 | 0.75 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ANXA2 | P07355 | 11/20 | 0.57 |
| ▸ | S100A10 | P60903 | 11/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18559076 | 0.86 | USP2 (1.00) | SMN1; SMN2USP2TSHRMAPTKMT2A | |
| SCHEMBL13832073 | 0.80 | MEN1 (0.69) | SMN1; SMN2USP2TSHRKMT2ACYP3A4 | |
| SCHEMBL14732159 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2USP2TSHRMAPTKMT2A | |
| SCHEMBL14732174 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2USP2TSHRMAPTKMT2A | |
| SCHEMBL14732156 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2TSHRMAPTKMT2ACYP3A4 | |
| SCHEMBL13831958 | 0.77 | CYP3A4 (0.65) | SMN1; SMN2USP2TSHRKMT2ACYP3A4 | |
| SCHEMBL13831273 | 0.77 | NPSR1 (0.69) | SMN1; SMN2USP2TSHRMAPTKMT2A | |
| SCHEMBL15983381 | 0.77 | SMN1; SMN2 (0.62) | SMN1; SMN2USP2TSHRMAPTKMT2A | |
| SCHEMBL15983303 | 0.77 | ALDH1A1 (0.66) | SMN1; SMN2USP2TSHRMAPTPOLB | |
| SCHEMBL14732106 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2USP2TSHRMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | UNIV VANDERBILT (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| US-10813355-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| US-10188105-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2019-01-29 | — | — | US | disclosed |
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4423/4885USP2 2348/4885TSHR 2971/4885 |
| US-10813355-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4355/4885USP2 2256/4885TSHR 3088/4885 |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4423/4885USP2 2348/4885TSHR 2971/4885 |
| US-10188105-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4404/4885USP2 2329/4885TSHR 2976/4885 |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4355/4885USP2 2256/4885TSHR 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.